Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase
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چکیده
منابع مشابه
Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase
Telomeres, the repetitive sequences at chromosomal ends, protect intact chromosomes. Telomeres progressively shorten through successive rounds of cell divisions, and critically shortened telomeres trigger senescence and apoptosis. The enzyme that elongates telomeres and maintains their structure is known as telomerase. The catalytic subunit of this enzyme (telomerase reverse transcriptase [TERT...
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ژورنال
عنوان ژورنال: Cancer Science
سال: 2015
ISSN: 1347-9032,1349-7006
DOI: 10.1111/cas.12806